The relationship between diabetes and coronary heart disease
- Filed under: Heart disease
- Date: Nov 8,2008
Diabetes is a metabolic disorder systemic diseases, easily lead to coronary heart disease. The Framingham study showed that patients with diabetes, both men and women, different age groups, the incidence of cardiovascular disease in diabetes group were higher than non-diabetic group. Between the sexes, men have more risk, but age-adjusted and control other risk factors for coronary heart disease, diabetic women suffering from coronary heart disease risk was higher than that of men, it was even reported that diabetes is coronary heart disease in women An independent risk factor.
Diabetic patients with coronary heart disease increased the incidence of the reasons is not yet clear, but the cause of diabetes atherosclerosis has been recognized. Most scholars believe, obesity, high blood pressure, hyperlipoproteinemia, high blood sugar, high-fiber protein hyperlipidemia (that is, the insulin resistance syndrome), these are inseparable. So that the fat on the body produce insulin resistance, in order to guarantee the normal level of blood glucose, insulin secretion of β cells to be several times higher than normal, or even several times the insulin to form a high hyperinsulinism, but also led to increased blood sugar, blood Triglyceride levels, HDL-C decreased, increased plasma fibrinogen, these are Atherosclerotic risk factors. At the same time, it has its own insulin to promote atherosclerosis, therefore, oral hypoglycemic agents methyl urine category, such as insulin injections or through various channels so that blood levels of insulin, which is likely to increase further hardening of the blood vessel diseases.
In addition, diabetes patients with coronary heart disease, coronary heart disease in some of the clinical symptoms of late or cover up. Because of diabetic neuropathy can affect any part of the nervous system, especially the ending, when the patient’s nerve damage, pain threshold increased in the event of a serious and myocardial ischemia, pain is also less than the typical logo, Do not even have symptoms of angina, the pain of the high incidence of myocardial infarction and shock, heart failure, sudden death is also more complications, more serious prognosis.
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